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When Dr. Teresa Sievers is found murdered in her kitchen, detectives struggle to find any leads until an unexpected tip changes everything; the woman who helped investigators speaks out.

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When a young mother disappears after leaving her infant in the care of her local pastor and his wife, Florida detectives search for her for five years, uncovering a web of secrets and lies.

A mystery in paradise unfolds when Sarm Heslop vanishes from her boyfriend's luxury yacht in the U.S. Virgin Islands; new details emerge on the case that made international headlines and left investigators with more questions than answers.

Computer antivirus pioneer John McAfee -- who remains a person of interest in a murder investigation -- discusses his new business and why he decided to stop running from the law.

Before time runs out, detectives race to find a Little Rock, Ark., realtor who went missing after showing a house.

When a California nursing student disappears during her hospital shift, her family works to locate her.

The disappearance of a 20-year-old honors student causes her family to fear the worst; decades later, the mystery is solved.

The FBI gets involved when a Virginia man's wife and son are kidnapped while vacationing in the Philippines, with a terrorist group demanding millions in ransom.

A matriarch's death leads to a prominent family from Texas being torn apart by decades of betrayal, greed and mistrust.

A woman's disappearance tears her young children apart; a sting operation catches an unlikely villain.

When a Pennsylvania man who was convinced his messy divorce put a target on his back is found stabbed to death, his friends and family realize he was right all along in predicting his own gruesome murder.

Detectives in Washington D.C. discover a puzzling connection between two women who disappeared two decades apart; an investigation reveals a sinister secret hidden along one of the busiest stretches of interstate in the country.

The five-year investigation into the death of a retired corrections officer, who was killed by antifreeze poisoning, reveals multiple suspects.

A look at the case of con man John Meehan, including interviews with his wife and her daughter, his ex-wife, law enforcement officers, and the Los Angeles Times reporter who shined a spotlight on the story.

When detectives track down the killer of a Las Vegas cocktail waitress and mother, it becomes clear that the investigation has just begun.

A woman's story about an abduction and murder helps reopen a decades-old case that has weighed heavy on a New York town.

When a young woman is found nearly murdered in her apartment, officials wonder if it is connected to the disappearance of a young woman in nearby Denver weeks earlier.

The question of a surgeon's whereabouts remains unanswered for five years after he disappears while on vacation in the Greek Islands with his wife, leaving behind financial ruin and mounting malpractice suits from patients in the U.S.

Lead investigators and family members speak about the murder of Colorado mother Kelsey Berreth, whose disappearance made national headlines after she was last seen grocery shopping on Thanksgiving in 2018.

Two decades after a Jacksonville, Fla., woman goes missing, her son solves the mystery that haunted his childhood.

When a University of Utah athlete is found murdered on campus, investigators learn that she had reached out to the campus police for help multiple times before her death.